Intractable colitis associated with chronic granulomatous disease

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ulcerative colitis associated with chronic granulomatous disease: case report

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Chronic granulomatous disease (CGD) is an autosomal recessive or X-linked disorder caused by NADPH oxidase deficiency leading to an impaired ability of reactive superoxide anion and metabolite formation and recurring severe bacterial and fungal infections, with a high mortality rate. Diarrhea, colitis, ileus, perirectal abscess formation and anal fissures are reported gastrointestinal findings ...

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Ulcerative colitis associated with chronic granulomatous disease: case report

Chronic Granulomatous Disease (CGD) is an inherited primary immunodeficiency disease which increases the body's susceptibility to infections caused by certain bacteria and fungi. CGD is a rare disease, caused by four genes, one type is 1X linked and the other three are "autosomal recessive". Although clinical presentation is variable, but characteristic features are recurrent pneumonia, lymphad...

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Colitis in chronic granulomatous disease.

BACKGROUND Involvement of the gut in chronic granulomatous disease (CGD) has been previously described and colitis highlighted. However, the nature and histopathology of the colitis are unclear and have been thought to be non-specific or similar to Crohn's disease. METHODS Seven patients with CGD, suffering from gastrointestinal symptoms were prospectively studied. RESULTS All patients had ...

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Colitis complicating chronic granulomatous disease. A clinicopathological case report.

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ژورنال

عنوان ژورنال: Journal of Medical Microbiology

سال: 2006

ISSN: 0022-2615,1473-5644

DOI: 10.1099/jmm.0.46722-0